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Study Reveals Genetic Adaptations to Micronutrient Deficiencies

10/4/2025

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Summary

Story summary

Large biobanks and public health data reveal population differences in micronutrient deficiency and toxicity driven by local adaptation.
Researchers find positive selection in gene sets related to micronutrient uptake and metabolism.
In Central-South Asian populations, adaptation in FXYD2 and MECOM may reduce magnesium toxicity.
The Maya of Central America show changes in iodine metabolism, reflecting adaptation to iodine-poor soils.

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Story summary

Large biobanks and public health data reveal population differences in micronutrient deficiency and toxicity driven by local adaptation.
Researchers find positive selection in gene sets related to micronutrient uptake and metabolism.
In Central-South Asian populations, adaptation in FXYD2 and MECOM may reduce magnesium toxicity.
The Maya of Central America show changes in iodine metabolism, reflecting adaptation to iodine-poor soils.