Story perspectives
Breakthrough: Type A Kidney Converted to Universal O for Transplant
10/4/2025
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Story summary
- University of British Columbia researchers successfully converted a kidney from type A to universal type O using special enzymes.
- This enabled the first human transplant of an enzyme-converted kidney, published in Nature Biomedical Engineering.
- Kidney functioned for two days.
- By day three, mild immune reactions appeared.
- Regulatory approval for clinical trials is the next step, led by Avivo Biomedical.
