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New EpiPlex Platform Revolutionizes RNA Methylation Profiling

10/4/2025

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Summary

Story summary

RNA modifications regulate gene expression in the epitranscriptome, with N6-methyladenosine (m6A) as the most prevalent.
Current methods like m6A RNA immunoprecipitation require substantial RNA input and show variability.
AlidaBio’s EpiPlexTM Platform enables scalable, accurate quantification of m6A and inosine with minimal RNA input.
Profiling RNA methylation in liver cancer shows global hypomethylation and helps detect dynamic RNA modifications.

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Story summary

RNA modifications regulate gene expression in the epitranscriptome, with N6-methyladenosine (m6A) as the most prevalent.
Current methods like m6A RNA immunoprecipitation require substantial RNA input and show variability.
AlidaBio’s EpiPlexTM Platform enables scalable, accurate quantification of m6A and inosine with minimal RNA input.
Profiling RNA methylation in liver cancer shows global hypomethylation and helps detect dynamic RNA modifications.