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Story perspectives

Breakthrough RLT Approved for Advanced Prostate Cancer Treatment

10/6/2025

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Story summary
  • RLT is approved for metastatic castration-resistant prostate cancer (CRPC) and may expand to genitourinary cancers, Praful Ravi says.
  • The PSMAddition trial seeks to test RLT earlier in treatment without hormone therapy.
  • Researchers are testing RLT in combination with chemotherapy and other therapies to improve outcomes.
  • PSMA-PET (prostate-specific membrane antigen) scans are standard before and during therapy.