Story perspectives
New Study Enhances Polymyxin Effectiveness Against Bacterial Dormancy
10/6/2025
42 4
1 of 1
Story summary
- Polymyxins disrupt the outer membranes of gram-negative bacteria, enabling the drug to kill.
- Imaging shows bacteria bulge and shed their protective armor, creating gaps for entry.
- Polymyxins are effective only against actively growing bacteria; dormant cells resist.
- Researchers aim to boost effectiveness by pairing polymyxins with armor-stimulating or dormancy-revival treatments.
- The study was published on September 29 in Nature Microbiology.
