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Aging Alters Brain Geometry, Heightening Alzheimer's Risk

10/7/2025

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Story summary
  • A University of California, Irvine study finds aging alters brain geometry, and this change is linked to memory and reasoning decline.
  • Inferior and anterior regions expand while superior and posterior regions compress.
  • These changes may stress the entorhinal cortex, a memory hub, elevating Alzheimer's risk.
  • The study suggests brain geometry could be an early biomarker for dementia risk.