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Study Links Alcohol Relapse to Brain's Stress Response

10/8/2025

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Story summary
  • A Scripps Research study links difficulty quitting alcohol to brain adaptations that ease stress and anxiety, fueling relapse.
  • Researchers identified active neurons in the paraventricular nucleus of the thalamus (PVT) that drive relapse behavior in rats.
  • The work suggests addiction stems from escaping negative states, not merely pursuing pleasure.
  • Britain reported a record high nearly 10,500 alcohol-related deaths in 2023.