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Story perspectives

Unlocking Genetic Insights to Revolutionize CAD Treatments

10/8/2025

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Story summary
  • Large-scale genome-wide association studies (GWAS) are advancing understanding of coronary artery disease (CAD) and related genetic factors.
  • Functional characterization of genetic variants is needed to improve treatments for CAD and type 2 diabetes (T2D).
  • Sex differences affect CAD presentation and management, while single-cell epigenomics and genomic-data integration advance personalized cardiovascular care.