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Psilocybin Therapy Shows Promise in Reducing Suicidal Thoughts

10/9/2025

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Summary

Story summary

Psilocybin therapy may reduce suicidal ideation in adults with psychiatric conditions, per a Therapeutic Advances in Psychopharmacology review.
A systematic review of nine trials (593 participants) found a small reduction in suicidal ideation with psilocybin.
Limitations include small samples and exclusion of high-risk individuals, limiting generalizability. No suicides or deaths occurred. Higher doses showed suicidal behavior.

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Story summary

Psilocybin therapy may reduce suicidal ideation in adults with psychiatric conditions, per a Therapeutic Advances in Psychopharmacology review.
A systematic review of nine trials (593 participants) found a small reduction in suicidal ideation with psilocybin.
Limitations include small samples and exclusion of high-risk individuals, limiting generalizability. No suicides or deaths occurred. Higher doses showed suicidal behavior.