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Story perspectives

Baltimore Leads Nation in Alarming Congenital Syphilis Rates

10/11/2025

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Story summary
  • Baltimore, Maryland, recorded 274 congenital syphilis cases per 100,000 live births in 2022, the highest rate nationwide.
  • Nationwide, cases rose from 60 to 110 per 100,000 births between 2020 and 2023.
  • Contributing factors include inadequate prenatal care and untreated infected pregnant women.
  • Johns Hopkins University received $225,000 to enhance testing and care.
  • The Centers for Disease Control and Prevention (CDC) cites systemic failures in prenatal syphilis testing and treatment.