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Philadelphia Scientist Carl June Advances CAR-T Therapy Research

10/12/2025

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Story summary
  • Carl June, a Philadelphia cancer scientist at the University of Pennsylvania, has received two prestigious CAR-T therapy awards.
  • His lab has advanced CAR-T research by optimizing solid-tumor approaches and by reinforcing Philadelphia as a biotech hub.
  • June's work shows CAR-T cells target blood cancers but face challenges in solid tumors, exhausting in two weeks.
  • The lab continues to study mechanisms that boost CAR-T efficacy, with promising results from recent trials.