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Study Links Brain Shape Changes to Cognitive Decline

10/13/2025

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Summary

Story summary

A study by researchers at the University of California, Irvine, and the University of La Laguna links changes in brain shape to cognitive decline.
They analyzed 2,603 MRI scans from people aged 30 to 97.
They found that uneven age-related brain-shape changes correlate with cognitive impairment.
The entorhinal cortex may be affected by these shifts, potentially contributing to Alzheimer's disease.

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Story summary

A study by researchers at the University of California, Irvine, and the University of La Laguna links changes in brain shape to cognitive decline.
They analyzed 2,603 MRI scans from people aged 30 to 97.
They found that uneven age-related brain-shape changes correlate with cognitive impairment.
The entorhinal cortex may be affected by these shifts, potentially contributing to Alzheimer's disease.