Back to today’s briefing

Story perspectives

GLP-1 Medications Slash Heart-Failure Mortality by 50%

10/13/2025

37 8

Summary

Story summary

A study presented at the European Society of Cardiology meeting finds GLP-1 medications may cut heart-failure mortality by 50%, led by Dr. Nils Krüger, and published in JAMA.
The analysis followed more than 90,000 adults with obesity, type 2 diabetes, and heart failure.
Starting semaglutide reduced hospitalization or death by 42%, with tirzepatide reducing it by 58%.

1 of 1

Story summary

A study presented at the European Society of Cardiology meeting finds GLP-1 medications may cut heart-failure mortality by 50%, led by Dr. Nils Krüger, and published in JAMA.
The analysis followed more than 90,000 adults with obesity, type 2 diabetes, and heart failure.
Starting semaglutide reduced hospitalization or death by 42%, with tirzepatide reducing it by 58%.