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Breakthrough Blood Test Revolutionizes Chronic Pain Diagnosis

10/15/2025

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Story summary
  • Dr. Alexander Niculescu and his team at the University of Arizona created a blood test to enhance diagnosis and treatment for chronic pain, which affects 20% of U.S. adults.
  • Their study identified 56 blood biomarkers associated with pain, including CD55 and ANXA1, and emphasized the link between chronic pain and mental health disorders.
  • Researchers from Stanford and NYU found that the gut microbe Bacteroides fragilis activates pain pathways related to inflammatory bowel disease (IBD) and developed nanoparticles to deliver a drug targeting pain receptors.