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Story perspectives

Study Links HPV Infection to Higher Depression Risk

10/16/2025

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Story summary
  • A United States study found a correlation between female HPV infection and increased depression risk, with inflammatory markers mediating the association.
  • Elevated levels of monocytes, lymphocytes, and neutrophils showed the strongest mediating effects.
  • Because the cross-sectional design limits causal conclusions, researchers call for future longitudinal studies to clarify these relationships.
  • Findings suggest integrating mental health assessments and inflammatory biomarker evaluations into HPV management to address physical and psychological health.