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Story perspectives

Study Reveals 5% Cancer Risk in General Population

10/17/2025

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Story summary
  • A study published in the Journal of the American Medical Association (JAMA) found that about 5.05% of individuals in a broad population carry pathogenic variants linked to cancer susceptibility.
  • The findings challenge the practice of limiting genetic testing to people with known risk factors.
  • The study, involving over 400,000 participants, supports population-level screening and integrating genomics into standard healthcare to improve cancer prevention and management.