Story perspectives

Managing Lupus Nephritis: Addressing Immunosuppressants' Side Effects

10/17/2025

Summary

Story summary

Immunosuppressants are essential for managing lupus nephritis, but their side effects can undermine patient trust and adherence.
Glucocorticoids can deplete vitamin D, cause bone loss, and raise cardiovascular risk.
Other immunosuppressants increase infection susceptibility.
Healthcare providers should proactively monitor and address these side effects, including regular vitamin D level checks and repletion.
Vitamin D is vital for immune regulation and deficiency is common in lupus.

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Story summary

Immunosuppressants are essential for managing lupus nephritis, but their side effects can undermine patient trust and adherence.
Glucocorticoids can deplete vitamin D, cause bone loss, and raise cardiovascular risk.
Other immunosuppressants increase infection susceptibility.
Healthcare providers should proactively monitor and address these side effects, including regular vitamin D level checks and repletion.
Vitamin D is vital for immune regulation and deficiency is common in lupus.