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Study Links Depo-Provera to Doubled Meningioma Risk

10/18/2025

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Summary

Story summary

The study found that Depo-Provera, a contraceptive manufactured by Pfizer, Inc., doubles the risk of meningioma compared with non-users.
The study analyzed over 61 million patient records.
Pfizer, Inc. faces more than 1,200 lawsuits from women alleging inadequate warnings.
A 2004 "black box" warning for bone density loss was added.
Concerns about meningioma have persisted.

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Story summary

The study found that Depo-Provera, a contraceptive manufactured by Pfizer, Inc., doubles the risk of meningioma compared with non-users.
The study analyzed over 61 million patient records.
Pfizer, Inc. faces more than 1,200 lawsuits from women alleging inadequate warnings.
A 2004 "black box" warning for bone density loss was added.
Concerns about meningioma have persisted.