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Breakthrough Nanoparticle Vaccine Shows Promise Against Aggressive Cancers

10/18/2025

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Story summary
  • Researchers at the University of Massachusetts Amherst developed a nanoparticle-based vaccine that targets aggressive cancers in mice, including melanoma, pancreatic cancer, and triple-negative breast cancer.
  • 88% of vaccinated mice remained cancer-free.
  • 80% of mice vaccinated against melanoma survived 250 days.
  • All unvaccinated mice died within seven weeks.
  • The vaccine uses a "super adjuvant" composed of lipid nanoparticles that enhance the immune response.