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Padcev and Keytruda Cut Bladder Cancer Risk by 60%

10/20/2025

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Story summary
  • The Padcev and Keytruda combination reduced the risk of recurrence, progression, or death by 60% in cisplatin-ineligible muscle-invasive bladder cancer.
  • Merck & Co., Pfizer Inc., and Astellas Pharma Inc. presented the results at the European Society of Medical Oncology conference in Berlin.
  • The combination’s survival remains unmeasured.
  • Over 80% survived at least two years on Padcev and Keytruda, compared with 60% for surgery alone.