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Story perspectives

Risperidone Linked to 28% Stroke Risk in Dementia Patients

10/20/2025

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Story summary
  • Risperidone raises stroke risk in older adults with dementia, showing a 28% increase among 28,403 patients.
  • Stroke incidence was similar for patients with or without prior stroke history, indicating elevated risk regardless of history.
  • Experts advise cautious risperidone use and prefer non-pharmacologic interventions to manage dementia symptoms.
  • A separate study links shingles infection to a 20–30% rise in major cardiovascular events, with vaccination reducing risk.