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Promising 80% Response in Melanoma Treatment Trial

10/21/2025

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Story summary
  • Sona Nanotech Inc. reported an 80% response rate in its first-in-human study of Targeted Hyperthermia Therapy (THT) for advanced, immunotherapy-resistant cutaneous metastatic melanoma.
  • The trial involved ten patients, with six achieving complete tumor clearance and two showing partial improvement within two weeks.
  • CEO David Regan noted that the results exceeded expectations, prompting plans for further clinical trials in Canada.
  • Safety data revealed one serious adverse event unrelated to THT, and two patients died from disease progression.
  • Sona will host a webinar to discuss the findings and future plans.