Story perspectives

New Tool Maps 1,300 Mouse Brain Regions, Reveals Surprises

10/21/2025

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Summary

Story summary

The Allen Institute for Brain Science and University of California, San Francisco (UCSF) developed CellTransformer to map mouse brain and identify 1,300 regions.
CellTransformer analyzes spatial transcriptomics from 3.9 million cells and classifies them into over 5,000 neuron types.
The team found the mouse brain has more regions than previously recognized.
Future work will test the functional relevance of these subregions and explore primate and human applications.

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Story summary

The Allen Institute for Brain Science and University of California, San Francisco (UCSF) developed CellTransformer to map mouse brain and identify 1,300 regions.
CellTransformer analyzes spatial transcriptomics from 3.9 million cells and classifies them into over 5,000 neuron types.
The team found the mouse brain has more regions than previously recognized.
Future work will test the functional relevance of these subregions and explore primate and human applications.