Story perspectives

Study Reveals Ketamine Infusions Offer No Extra Benefits

10/23/2025

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Summary

Story summary

A study published in JAMA Psychiatry found repeated ketamine infusions do not add benefits over standard inpatient care for major depression.
The trial involved 65 participants and compared ketamine to midazolam, with no significant differences in depression, cognition, or quality of life.
Researchers noted many participants correctly guessed their treatment, which may have inflated perceived effects, underscoring cautious use of this treatment in Ireland.

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Story summary

A study published in JAMA Psychiatry found repeated ketamine infusions do not add benefits over standard inpatient care for major depression.
The trial involved 65 participants and compared ketamine to midazolam, with no significant differences in depression, cognition, or quality of life.
Researchers noted many participants correctly guessed their treatment, which may have inflated perceived effects, underscoring cautious use of this treatment in Ireland.