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Japan Trials Pioneering Rectal Oxygen Delivery Method

10/23/2025

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Summary

Story summary

Researchers in Japan conducted the first human trial of enteral ventilation, a method delivering oxygen rectally.
The study enrolled 27 healthy men who tolerated one hour with the non-oxygenated liquid perfluorodecalin.
Participants experienced mild bloating and no serious side effects.
Future trials will test oxygenated liquid to determine whether it raises blood oxygen levels, building on earlier animal studies.

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Story summary

Researchers in Japan conducted the first human trial of enteral ventilation, a method delivering oxygen rectally.
The study enrolled 27 healthy men who tolerated one hour with the non-oxygenated liquid perfluorodecalin.
Participants experienced mild bloating and no serious side effects.
Future trials will test oxygenated liquid to determine whether it raises blood oxygen levels, building on earlier animal studies.