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Study Reveals Aging Biomarkers in Dogs' Protein Metabolism

10/24/2025

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Summary

Story summary

Researchers from the Dog Aging Project identify post-translationally modified amino acids (ptmAAs) as aging biomarkers in dogs, in a study involving nearly 800 dogs.
The metabolites increase with age, indicating changes in protein metabolism and kidney function.
The integrity of the hypothalamic-pituitary-gonadal axis is linked to reduced frailty in aging male dogs, suggesting hormonal health could inform veterinary practices.

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Story summary

Researchers from the Dog Aging Project identify post-translationally modified amino acids (ptmAAs) as aging biomarkers in dogs, in a study involving nearly 800 dogs.
The metabolites increase with age, indicating changes in protein metabolism and kidney function.
The integrity of the hypothalamic-pituitary-gonadal axis is linked to reduced frailty in aging male dogs, suggesting hormonal health could inform veterinary practices.