Story perspectives

Study Links Tobacco-Cannabis Combo to Addiction Risks

10/25/2025

Summary

Story summary

McGill University researchers report that combining tobacco with cannabis elevates the brain enzyme FAAH, based on a study of 13 participants.
Higher FAAH levels correlate with increased tobacco use, suggesting tobacco may sensitize the endocannabinoid system.
The biochemical change could heighten vulnerability to stress and addiction.
The researchers call for larger studies to confirm the findings and to explore FAAH as a potential therapeutic target for cannabis use disorder.

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Story summary

McGill University researchers report that combining tobacco with cannabis elevates the brain enzyme FAAH, based on a study of 13 participants.
Higher FAAH levels correlate with increased tobacco use, suggesting tobacco may sensitize the endocannabinoid system.
The biochemical change could heighten vulnerability to stress and addiction.
The researchers call for larger studies to confirm the findings and to explore FAAH as a potential therapeutic target for cannabis use disorder.