Story perspectives

Japan's First Human Trial of Rectal Oxygen Delivery

10/26/2025

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Summary

Story summary

The first human trial of enteral ventilation, a rectal oxygen-delivery method, was conducted by Japanese researchers and published in Med.
The study enrolled 27 healthy male volunteers who tolerated up to 1,000 milliliters of non-oxygenated perfluorodecalin without serious side effects.
The researchers aim to evaluate the method's effectiveness for patients with respiratory failure in future trials.
The team has previously received the Ig Nobel Prize for their unconventional research.

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Story summary

The first human trial of enteral ventilation, a rectal oxygen-delivery method, was conducted by Japanese researchers and published in Med.
The study enrolled 27 healthy male volunteers who tolerated up to 1,000 milliliters of non-oxygenated perfluorodecalin without serious side effects.
The researchers aim to evaluate the method's effectiveness for patients with respiratory failure in future trials.
The team has previously received the Ig Nobel Prize for their unconventional research.