Story perspectives

New Device Revolutionizes Treatment for Pulmonary Embolism

10/27/2025

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Summary

Story summary

The STORM-PE trial, presented at TCT 2025, found that mechanical thrombectomy with the Lightning Flash device reduced the RV/LV ratio at 48 hours more than standard anticoagulation in 100 patients with acute intermediate-high-risk pulmonary embolism.
There were no device-related complications reported in the trial.
Investigators say the findings could reshape PE treatment guidelines, noting that practices have not changed in over a decade.
Further results from related trials are expected soon.

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Story summary

The STORM-PE trial, presented at TCT 2025, found that mechanical thrombectomy with the Lightning Flash device reduced the RV/LV ratio at 48 hours more than standard anticoagulation in 100 patients with acute intermediate-high-risk pulmonary embolism.
There were no device-related complications reported in the trial.
Investigators say the findings could reshape PE treatment guidelines, noting that practices have not changed in over a decade.
Further results from related trials are expected soon.