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Story perspectives

Mpox Clade Ib Spreads in Europe, Vaccination Urged

10/28/2025

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Story summary
  • Mpox caused by the clade Ib strain is spreading in Europe and the United States, with 16 UK cases and cases in Portugal, Spain, Italy, and the Netherlands, per the UK Health Security Agency.
  • Dr. Katy Sinka, a health official, emphasizes vaccination, especially for people with multiple sexual partners.
  • The vaccine is 75–80% effective against clade II; clade Ib efficacy is unknown.
  • The UK transmission risk remains low to medium.