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UC Berkeley Study: Oxytocin Boosts Lifespan by 73% in Mice

10/29/2025

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Summary

Story summary

The University of California, Berkeley, study finds that a combination of oxytocin and Alk5 inhibitor (A5i) extends lifespan by 73% in frail male mice, targeting two aging pathways and improving physical performance.
Benefits appeared in male mice only, and female mice did not gain.
The study suggests potential anti-aging treatments, noting oxytocin is already approved for other uses and the work is published in Aging.

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Story summary

The University of California, Berkeley, study finds that a combination of oxytocin and Alk5 inhibitor (A5i) extends lifespan by 73% in frail male mice, targeting two aging pathways and improving physical performance.
Benefits appeared in male mice only, and female mice did not gain.
The study suggests potential anti-aging treatments, noting oxytocin is already approved for other uses and the work is published in Aging.