Story perspectives
Aging Alters T Cell Behavior, Weakens Immunity in Seniors
10/30/2025
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Story summary
- The Allen Institute reports that aging alters T cell behavior, weakening immune responses and potentially vaccine efficacy in older adults.
- Over a two-year study, researchers compared people aged 55–65 with younger adults and found a shift toward a T helper 2 (TH2) bias in memory T cells.
- This bias reduces antibody production and overall immune function.
- The findings support tailored vaccine strategies to protect older adults.
