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New Study Links Brain Shape Changes to Early Dementia Signs

11/1/2025

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Summary

Story summary

The study by neuroscientists from the University of California, Irvine, and the University of La Laguna shows that brain-shape changes may indicate early signs of dementia before memory loss.
Researchers analyzed over 2,600 MRI scans and found that brain regions, especially the entorhinal cortex, shrink or expand unevenly with age, correlating with cognitive decline.
The findings suggest shape-based imaging could serve as an early screening tool for dementia.
Maintaining brain health through mental activity, exercise, a healthy diet, and good sleep hygiene can reduce dementia risk.

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Story summary

The study by neuroscientists from the University of California, Irvine, and the University of La Laguna shows that brain-shape changes may indicate early signs of dementia before memory loss.
Researchers analyzed over 2,600 MRI scans and found that brain regions, especially the entorhinal cortex, shrink or expand unevenly with age, correlating with cognitive decline.
The findings suggest shape-based imaging could serve as an early screening tool for dementia.
Maintaining brain health through mental activity, exercise, a healthy diet, and good sleep hygiene can reduce dementia risk.