Story perspectives

American Academy of Pediatrics Rejects Routine Leucovorin for Autism

11/1/2025

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Summary

Story summary

The American Academy of Pediatrics announced on October 31, 2025 that it does not recommend routine leucovorin use in children with autism due to insufficient evidence.
The guidance follows increased demand from parents after a September 2025 press conference by U.S. health officials.
The U.S. Food and Drug Administration plans to update leucovorin's labeling for cerebral folate deficiency.
Dr. Kristin Sohl highlighted the importance of evidence-based interventions for autistic children.

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Story summary

The American Academy of Pediatrics announced on October 31, 2025 that it does not recommend routine leucovorin use in children with autism due to insufficient evidence.
The guidance follows increased demand from parents after a September 2025 press conference by U.S. health officials.
The U.S. Food and Drug Administration plans to update leucovorin's labeling for cerebral folate deficiency.
Dr. Kristin Sohl highlighted the importance of evidence-based interventions for autistic children.