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New Brain Abnormality Linked to Anxiety Revealed

11/1/2025

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Story summary
  • Fujita Health University and the Tokyo Metropolitan Institute of Medical Science identified a brain abnormality linked to anxiety, dubbed 'hyper-maturity,' with excessive hippocampal maturation.
  • The team published in Neuropsychopharmacology after analyzing gene expression in 17 datasets from neuropsychiatric mouse models.
  • They propose hyper-maturity may be a common molecular signature across anxiety and depression and aim to explore mechanisms for new therapies.