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Aging Impacts Male Brains More Than Female Brains

11/3/2025

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Summary

Story summary

A study in Proceedings of the National Academy of Sciences (PNAS) finds aging harms male brains more than female brains.
Led by University of Oslo scientists, the team analyzed 12,638 MRI scans from 4,726 healthy participants aged 17–95.
Results show men suffer greater brain-structure declines, especially in memory and visual processing regions.
The study notes Alzheimer’s prevalence in women is not explained by normal aging.
Women do not decline faster.

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Story summary

A study in Proceedings of the National Academy of Sciences (PNAS) finds aging harms male brains more than female brains.
Led by University of Oslo scientists, the team analyzed 12,638 MRI scans from 4,726 healthy participants aged 17–95.
Results show men suffer greater brain-structure declines, especially in memory and visual processing regions.
The study notes Alzheimer’s prevalence in women is not explained by normal aging.
Women do not decline faster.