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New Genetic Test Predicts Weight Loss Success Post-Surgery

11/5/2025

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Summary

Story summary

MyPhenome, a genetic biomarker test, predicts semaglutide response after bariatric surgery, researchers reported at ObesityWeek in Atlanta.
The study followed 68 adults undergoing Roux-en-Y gastric bypass or sleeve gastrectomy.
At six months, hungry gut positive participants lost 10% body weight versus 5.2% for negatives.
The test showed 96% sensitivity and 90% negative predictive value, signaling high accuracy.
Researchers say the approach supports precision medicine in obesity, especially for diverse populations.

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Story summary

MyPhenome, a genetic biomarker test, predicts semaglutide response after bariatric surgery, researchers reported at ObesityWeek in Atlanta.
The study followed 68 adults undergoing Roux-en-Y gastric bypass or sleeve gastrectomy.
At six months, hungry gut positive participants lost 10% body weight versus 5.2% for negatives.
The test showed 96% sensitivity and 90% negative predictive value, signaling high accuracy.
Researchers say the approach supports precision medicine in obesity, especially for diverse populations.