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Louisville's Star RB Isaac Brown Injured, Keyjuan Steps Up

11/5/2025

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Summary

Story summary

Louisville running back Isaac Brown is sidelined with a leg injury from the Week 10 win over Virginia Tech, missing the game against California.
Head coach Jeff Brohm said Brown's return this season remains possible.
Brown has 782 rushing yards and six touchdowns in seven games, making him the ACC's second-leading rusher.
Keyjuan Brown is expected to step up as Louisville's lead back as Louisville pursues a second ACC Championship.

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Story summary

Louisville running back Isaac Brown is sidelined with a leg injury from the Week 10 win over Virginia Tech, missing the game against California.
Head coach Jeff Brohm said Brown's return this season remains possible.
Brown has 782 rushing yards and six touchdowns in seven games, making him the ACC's second-leading rusher.
Keyjuan Brown is expected to step up as Louisville's lead back as Louisville pursues a second ACC Championship.