Story perspectives

Long-Term Melatonin Use Linked to Heart Failure Risks

11/7/2025

Summary

Story summary

A study presented at the American Heart Association's Scientific Sessions 2025 linked melatonin use to risks of heart failure and death.
Researchers analyzed data from over 130,000 adults with insomnia and found long-term use (>=1 year) raised heart-failure risk by 90%.
Hospitalization rates for heart failure were nearly three times higher among long-term melatonin users.
The study did not establish a direct cause-and-effect relationship and called for further research.

1 of 1

Story summary

A study presented at the American Heart Association's Scientific Sessions 2025 linked melatonin use to risks of heart failure and death.
Researchers analyzed data from over 130,000 adults with insomnia and found long-term use (>=1 year) raised heart-failure risk by 90%.
Hospitalization rates for heart failure were nearly three times higher among long-term melatonin users.
The study did not establish a direct cause-and-effect relationship and called for further research.