Story perspectives

Revolutionary Gene Editing System Transforms Tomato Breeding

11/7/2025

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Summary

Story summary

A Sejong University team in South Korea developed a TRV-mediated genome editing system for tomatoes, producing heritable mutants without tissue culture.
The method uses a tomato-specific sgRNA scaffold to target the SlPDS gene, achieving mutation rates of 20–71% in systemic leaves.
The approach enables rapid gene editing, benefiting tomato breeders and molecular biologists.
Grafting techniques are explored to enable gene editing in cocoa and coffee, which resist conventional methods.

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Story summary

A Sejong University team in South Korea developed a TRV-mediated genome editing system for tomatoes, producing heritable mutants without tissue culture.
The method uses a tomato-specific sgRNA scaffold to target the SlPDS gene, achieving mutation rates of 20–71% in systemic leaves.
The approach enables rapid gene editing, benefiting tomato breeders and molecular biologists.
Grafting techniques are explored to enable gene editing in cocoa and coffee, which resist conventional methods.