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Alzheimer's Disrupts Nerve-Blood Vessel Communication, Impairs Metabolism

11/9/2025

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Story summary
  • A study in the Journal of Lipid Research shows that Alzheimer's disease disrupts communication between sympathetic nerves and blood vessels in adipose tissue, linking to metabolic issues.
  • Researchers at Houston Methodist found that healthy fat tissue has nerves closely aligned with blood vessels, while Alzheimer's in mice decouples them and impairs metabolism.
  • The findings point to new avenues for treating autonomic dysfunction in Alzheimer's patients.