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Story summary
- A study presented at the American Heart Association’s Scientific Sessions 2025 links long-term melatonin use to a 90% higher risk of heart failure among adults with insomnia.
- The analysis used data from more than 130,000 patients and found melatonin users had a 3.5-fold higher risk of heart failure hospitalization and nearly double the all-cause mortality.
- Researchers caution that the findings do not establish causation.
