Story perspectives
CRISPR Breakthrough: Scientists Aim to Reverse Gout
11/9/2025
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Story summary
- Georgia State University scientists used CRISPR gene editing to reactivate the ancient uricase enzyme in human liver cells, which lowers uric acid and could reverse gout.
- Restoration of uricase lowers uric acid and prevents fat buildup.
- Future studies will explore animal models and human trials to address safety and ethics.
