Story perspectives

New Pan-Cancer Gene Panel Standardizes Testing in the UK

11/9/2025

Summary

Story summary

A new consensus-based pan-cancer gene panel has been developed for UK cancer genomics to standardize testing across cancer types.
The panel covers 99 essential genes and markers such as tumor mutational burden (TMB) and microsatellite instability (MSI).
It aims to identify actionable mutations and improve patient access to clinical trials.
Delphi methodology, conducted through a three-round process, has limitations such as participant fatigue and knowledge gaps that may affect robustness.

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Story summary

A new consensus-based pan-cancer gene panel has been developed for UK cancer genomics to standardize testing across cancer types.
The panel covers 99 essential genes and markers such as tumor mutational burden (TMB) and microsatellite instability (MSI).
It aims to identify actionable mutations and improve patient access to clinical trials.
Delphi methodology, conducted through a three-round process, has limitations such as participant fatigue and knowledge gaps that may affect robustness.