Story perspectives
Genetic Links Found Between Cannabis Use and Addiction Risks
11/10/2025
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Story summary
- A 2025 study in Molecular Psychiatry links variations in the CADM2 and GRM3 genes to cannabis use behaviors and the risk of cannabis use disorder.
- An analysis of data from 131,895 individuals shows genetic risks for cannabis use overlap with those for other substance use disorders.
- THC addiction is associated with higher mental-health risks, especially in genetically vulnerable individuals.
