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Metformin May Hinder Exercise Benefits for Diabetics

11/13/2025

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Summary

Story summary

Rutgers University researchers found that metformin may blunt the cardiovascular benefits of exercise.
In a 16-week trial involving 72 adults at risk for metabolic syndrome, metformin users showed no improvement in blood vessel function or aerobic fitness, unlike placebo participants.
Lead researcher Steven Malin of Rutgers University said the interaction could undermine diabetes management, since exercise typically lowers blood sugar and improves physical function.

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Story summary

Rutgers University researchers found that metformin may blunt the cardiovascular benefits of exercise.
In a 16-week trial involving 72 adults at risk for metabolic syndrome, metformin users showed no improvement in blood vessel function or aerobic fitness, unlike placebo participants.
Lead researcher Steven Malin of Rutgers University said the interaction could undermine diabetes management, since exercise typically lowers blood sugar and improves physical function.