Story perspectives
New Microglia Types Reveal Potential Anxiety Treatment
11/15/2025
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Story summary
- Researchers at the University of Utah identify two microglia types that influence anxiety, affecting about 20% of Americans.
- Non-Hoxb8 microglia increase anxiety.
- Hoxb8 microglia reduce anxiety.
- Mice lacking Hoxb8 microglia show heightened anxiety.
- Mice with both microglia types display normal anxiety-related behavior, suggesting a potential shift in treatment toward microglia.
