Story perspectives

Breakthrough Molecule Targets Cancer RNA, Promises New Therapy

11/16/2025

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Summary

Story summary

Researchers at the Hebrew University of Jerusalem developed a drug-like molecule that targets TERRA, an RNA essential for some cancer cells.
Using the RIBOTAC technique, the molecule locates TERRA and degrades it without harming healthy RNA.
In experiments, it significantly reduced TERRA levels in cancer cell lines and inhibited their growth.
The findings imply a shift toward RNA-targeted cancer therapy, with further studies and potential human trials within three years.

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Story summary

Researchers at the Hebrew University of Jerusalem developed a drug-like molecule that targets TERRA, an RNA essential for some cancer cells.
Using the RIBOTAC technique, the molecule locates TERRA and degrades it without harming healthy RNA.
In experiments, it significantly reduced TERRA levels in cancer cell lines and inhibited their growth.
The findings imply a shift toward RNA-targeted cancer therapy, with further studies and potential human trials within three years.