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Study Links Limbic Disruptions to Severe ADHD Symptoms

11/16/2025

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Story summary
  • The study, published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, finds early limbic disruptions in children and adolescents with ADHD.
  • Analyses of 169 participants show more severe ADHD symptoms correlated with lower limbic connectivity.
  • The researchers used diffusion MRI scans across three time points to confirm these features are stable.
  • Findings indicate early limbic white matter differences may influence ADHD symptom severity throughout development, supporting a dimensional view.