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Genetic Study Links Early-Onset Depression to Suicide Risk

11/17/2025

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Summary

Story summary

A Nature Genetics study analyzes data from over 150,000 individuals and shows major depression has age-of-onset genetic roots.
Early-onset depression before age 25 shows a stronger genetic basis tied to brain development and higher suicide attempts.
The study identifies twelve regions for early-onset depression and two for late-onset.
Findings suggest genetic information could help identify individuals at high risk for suicide and guide treatment, with diverse populations research needed.

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Story summary

A Nature Genetics study analyzes data from over 150,000 individuals and shows major depression has age-of-onset genetic roots.
Early-onset depression before age 25 shows a stronger genetic basis tied to brain development and higher suicide attempts.
The study identifies twelve regions for early-onset depression and two for late-onset.
Findings suggest genetic information could help identify individuals at high risk for suicide and guide treatment, with diverse populations research needed.